N-(tert-butoxycarbonyl)-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-L-phenylalanine
Boc-p-amino-Phe(Fmoc)-OH
CAS: 114346-31-5
Molecular Formula: C29H30N2O6
N-(tert-butoxycarbonyl)-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-L-phenylalanine - Names and Identifiers
| Name | Boc-p-amino-Phe(Fmoc)-OH |
| Synonyms | Boc-Phe(4-NHFmoc)-OH BOC-PHE(P-NHFMOC)-OH BOC-PHE(4-NHFMOC)-OH BOC-P(NH-FMOC)-L-PHE-OH Boc-p-amino-Phe(Fmoc)-OH boc-l-4-aminophenylalanine(fmoc) (S)-BOC-(4-FMOC-AMINO)-PHENYLALANINE N-ALPHA-BOC-L-4-(FMOC-AMINO)-PHENYLALANINE N-ALPHA-T-BUTOXYCARBONYL-[4-(9-FLUORENYLMETHOXYCARBONYLAMINO)]-L-PHENYLALANINE N-(tert-butoxycarbonyl)-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-L-phenylalanine N-ALPHA-TERT-BUTYLOXYCARBONYL-4-(9-FLUORENYLMETHYLOXYCARBONYL)AMINO-L-PHENYLALANINE (S)-3-(4-(((9H-fluoren-9-yl)methoxy)carbonylamino)phenyl)-2-(tert-butoxycarbonylamino)propanoic acid |
| CAS | 114346-31-5 |
| InChI | InChI=1/C29H30N2O6/c1-29(2,3)37-28(35)31-25(26(32)33)16-18-12-14-19(15-13-18)30-27(34)36-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,30,34)(H,31,35)(H,32,33)/t25-/m0/s1 |
N-(tert-butoxycarbonyl)-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-L-phenylalanine - Physico-chemical Properties
| Molecular Formula | C29H30N2O6 |
| Molar Mass | 502.56 |
| Density | 1.280±0.06 g/cm3(Predicted) |
| Boling Point | 671.0±55.0 °C(Predicted) |
| Flash Point | 359.6°C |
| Vapor Presure | 6.37E-19mmHg at 25°C |
| Appearance | Solid |
| pKa | 3.90±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.622 |
N-(tert-butoxycarbonyl)-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-L-phenylalanine - Risk and Safety
| WGK Germany | 3 |
| HS Code | 29242990 |
N-(tert-butoxycarbonyl)-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-L-phenylalanine - Introduction
Boc-L-4-(9-fluorenylmethoxycarbonylamino) phenylalanine is an organic compound whose chemical formula is C26H29NO5. It has the following properties:
1. Appearance: white or almost white crystalline powder.
2. Solubility: Soluble in some organic solvents, such as dimethylformamide, dichloromethane and methanol.
3. Stability: Stable at room temperature, but avoid prolonged exposure to moisture and light.
Boc-L-4-(9-fluorenylmethoxycarbonylamino) phenylalanine is commonly used in the process of peptide synthesis or drug synthesis in organic synthesis, as the introduction of protecting groups or functional groups. It can be used to modify amino acids, enhance their pharmaceutical activity or improve their bioavailability.
The compound can be synthesized by the following methods:
First, a Boc protecting group is introduced into phenylalanine to obtain Boc-L-phenylalanine. Then, 9-fluorenomethylamine and dioxofluoroformic acid are reacted with Boc-L-phenylalanine to produce Boc-L-4-(9-fluorenylmethoxycarbonylamino) phenylalanine. Finally, the desired product can be purified by crystallization or column chromatography.
When using Boc-L-4-(9-fluorenylmethoxycarbonylamino) phenylalanine, the following safety information should be noted:
1. The compound may be irritating to skin, eyes and mucous membranes, and protective measures should be taken when contacting.
2. During the operation, avoid inhaling the dust and the vapor of the solution, and operate in a well-ventilated place.
3. should be stored in a dry, cool place, away from the fire and oxidant.
When using the compound in the laboratory, you should follow the relevant safety procedures and wear personal protective equipment when necessary. Please ensure that you understand and comply with local laws and regulations and consult a professional for advice.
1. Appearance: white or almost white crystalline powder.
2. Solubility: Soluble in some organic solvents, such as dimethylformamide, dichloromethane and methanol.
3. Stability: Stable at room temperature, but avoid prolonged exposure to moisture and light.
Boc-L-4-(9-fluorenylmethoxycarbonylamino) phenylalanine is commonly used in the process of peptide synthesis or drug synthesis in organic synthesis, as the introduction of protecting groups or functional groups. It can be used to modify amino acids, enhance their pharmaceutical activity or improve their bioavailability.
The compound can be synthesized by the following methods:
First, a Boc protecting group is introduced into phenylalanine to obtain Boc-L-phenylalanine. Then, 9-fluorenomethylamine and dioxofluoroformic acid are reacted with Boc-L-phenylalanine to produce Boc-L-4-(9-fluorenylmethoxycarbonylamino) phenylalanine. Finally, the desired product can be purified by crystallization or column chromatography.
When using Boc-L-4-(9-fluorenylmethoxycarbonylamino) phenylalanine, the following safety information should be noted:
1. The compound may be irritating to skin, eyes and mucous membranes, and protective measures should be taken when contacting.
2. During the operation, avoid inhaling the dust and the vapor of the solution, and operate in a well-ventilated place.
3. should be stored in a dry, cool place, away from the fire and oxidant.
When using the compound in the laboratory, you should follow the relevant safety procedures and wear personal protective equipment when necessary. Please ensure that you understand and comply with local laws and regulations and consult a professional for advice.
Last Update：2024-04-09 21:21:28
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Product Name: Boc-L-(4-Fmoc)Aminophenylalanine Visit Supplier Webpage Request for quotation
CAS: 114346-31-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 114346-31-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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